PBDE Flame Retardants and Thyroid Hormones during Pregnancy

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PBDE Flame Retardants and Thyroid Hormones during Pregnancy

Chevrier et al. (2010) assessed the association between 10 polybrominated diphenyl ethers (PBDEs) and free and total thyroxine (T4) and thyroid-stimulating hormone (TSH) in 270 women around the 27th week of gestation. They concluded that PBDEs are associated with lower TSH levels during pregnancy, but several factors that likely influenced the results were not considered in their analysis. Norm...

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Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy

BACKGROUND Polybrominated diphenyl ethers (PBDEs) are chemical additives used as flame retardants in commercial products. PBDEs are bioaccumulative and persistent and have been linked to several adverse health outcomes. OBJECTIVES This study leverages an ongoing pregnancy cohort to measure PBDEs and PBDE metabolites in serum collected from an understudied population of pregnant women late in ...

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Polybrominated Diphenyl Ether (PBDE) Flame Retardants and Thyroid Hormone during Pregnancy

BACKGROUND Human exposure to polybrominated diphenyl ether (PBDE) flame retardants has increased exponentially over the last three decades. Animal and human studies suggest that PBDEs may disrupt thyroid function. Although thyroid hormone (TH) of maternal origin plays an essential role in normal fetal brain development, there is a paucity of human data regarding associations between exposure to...

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Non - PBDE Flame Retardants in the Environment and in People

We are all aware of the ubiquity of polybrominated diphenyl ether (PBDE) flame retardants in the environment and in people; indeed, there have been several reviews on the subject (among others, see Hites, 2004; Hale et al., 2006; Law et al., 2006). In addition to PBDEs, there is a developing body of knowledge on the environmental presence of hexabromocyclododecanes (HBCDs) (see Covaci et al., 2...

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Brominated Flame Retardants (PBDE and PBB) in Sludge – a Problem?

Preface In the autumn of 1999, the presence of brominated flame retardants in sewage sludge aroused medial attention in Sweden. As a result of this, LRF (The farmers organisation) recommended their members to renounce receiving and using sludge as a fertilizer. According to preliminary risk evaluations made at the same time, no obvious risk could be detected. VAV took the initiative to do a fur...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 2010

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.1002782